06.07.2015

Glaucoma gene "identified in new study"

Glaucoma gene "identified in new study"

Research has identified a new candidate gene responsible for primary open angle glaucoma (POAG), the most common form of the eye disorder.

Experts from Vanderbilt University and the University of Florida examined the genetic code of beagles, which are the only naturally-occurring animal model for human POAG, to determine if any one specific gene could be to blame.

The research, which was published in the open-access journal PLoS Genetics, claimed that a mutation of the ADAMTS10 gene could be responsible for the onset of glaucoma in beagles.

This is because ADAMTS10 seems to play a role in aqueous outflow regulation, which can lead to the development of POAG.

Dr John Kuchtey, the paper"s first author, commented: "If this gene truly plays a role in aqueous outflow regulation, we can begin to look at it – or its molecular partners – as targets for treatments."

Recent research carried out by the Erasmus Medical Center in the Netherlands and published in the Archives of Ophthalmology claimed obese women may have a lower risk of developing open-angle glaucoma
 

by Emily Tait


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